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Velo-Cardio-Facial Syndrome (VCFS) is a genetic disorder caused by the deletion of part of chromosome 22. It occurs in approximately one in 4000 births and there are now more than 100 physical phenotypic features reported. VCFS affects every major system in the body and this 2005 book was the first to describe its full clinical impact. It has been authored by leading international VCFS clinicians/researchers. The focus is on clinical issues with chapters devoted to psychiatric disorders (with the sufferer showing very high levels of schizophrenia), neuroimaging, speech and language disorders, as well as cardiac, ENT, gastrointestinal, ophthalmic and urological manifestations. Molecular genetics, immunodeficiency and genetic counselling are also covered, and practical approaches to diagnosis and treatment described. As VCFS is seen as a paradigm for other microdeletion disorders, this book will not just appeal to clinicians seeing VCFS patients, but also to those interested in other genetic disorders.
This book draws on the established European guidelines from the ESC that address the key issues in sudden cardiac death, such as identifying individuals at risk prior to an episode of a ventricular tachyarrhythmia or a sudden cardiac arrest, and responding in a timely fashion to the person suffering the event out-of-the-hospital. It presents an update on what is known about sudden cardiac arrest, from basic experimental studies to clinical trials, and serves as a complement to the ESC Core Syllabus on this subject.<br><p><br><p>Topics include epidemiology, genetics, arrhythmogenic mechanisms, risk stratification, autonomic nervous system and phenotypes. Disease states and special populations are also covered, as well as drug, device and ablation treatments, and cost effectiveness. All chapters are co-authored by experts from both Europe and the US.<br><p><b>The ESC Education Series</b><br>This book is part of the ESC Education Series. The series is designed to provide medical professionals with the latest information about the understanding, diagnosis and management of cardiovascular diseases. Where available, management recommendations are based on the established European Guidelines, which encompass the best techniques to use with each cardiac disease. Throughout the series, the leading international opinion leaders have been chosen to edit and contribute to the books. The information is presented in a succinct and accessible format with a clinical focus.
Lavishly illustrated and easy to use, this comprehensive guide covers every aspect of fetal heart examination and all major cardiac malformations. World-renowned experts in the field, Drs. Abuhamad and Chaoui, world-renowned experts in the field, have meticulously updated and expanded this third edition while maintaining its systematic and methodical approach. New chapters, 25% new images, and a practical, concise format make this reference indispensable for both physicians and sonographers in the detection of congenital heart disease.
financial markets suggests that factors such as differences in capital requirements, limi- tations on size or on the range of financial activities in which firms can engage, govern- ment guarantee arrangements for deposits or payments, and reporting or disclosure requirements can have important effects on the efficiency of industrial and commercial firms and thus on the international competitive positions of major sectors of the U.S. economy. Regulatory and tax policies must therefore take into account effects on inter- national competitive positions in addition to domestic concerns. The articles in this issue analyze differences in market organization and regulation across countries and examine how efficiency in producing financial services is influenced by these differences. These articles were presented and discussed at a conference sponsored by the Amer- ican Enterprise Institute in Washington, D.C., on May 31 and June 1, 1990. This confer- ence on International Competitiveness in Financial Services brought to the attention of Washington policy officials these analyses by leading scholars in finance. Publication of these studies and critiques in the Journal of Financial Services Research is intended to stimulate further interest in research on these important issues.
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